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Welcome to
SCHIZOPHRENIA.LIFE

An essential resource for healthcare
professionals treating people with
schizophrenia.

Find out what’s NEW

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Welcome to
SCHIZOPHRENIA.LIFE

An essential resource for healthcare professionals treating people with schizophrenia.

Find out what’s NEW

Mastering the Diagnosis of Schizophrenia

Since no blood test or brain scan exists for schizophrenia, a great deal of attention must be paid to the constellation of symptoms that best define schizophrenia to ensure accurate diagnosis.

How do you diagnose?

References

  1. American Psychiatric Association. DSM-5 Diagnostic Classification in Diagnostic and Statistical Manual of Mental Disorders (2013). doi:10.1176/ appi.books.9780890425596.x00 diagnosticclassification
  2. WHO. International statistical classification of diseases and related health problems – 10th revision. World Heal. Organ. (2011).
ICD and DSM Criteria for schizophrenia - comparison
ICD and DSM Criteria for schizophrenia - comparison


What is the Connection Between Inflammation and Schizophrenia?

Maternal Immune ActivationMaternal Immune Activation

Over the last few decades there has been increasing interest in early intervention and prevention of schizophrenia, a topic recently reviewed by Hashimoto and published in the Current Psychiatry Reports journal.1

References

  1. Hashimoto. Current Psychiatry Reports. 2019;21:75

Interview with Prof. LLORCA

Latest trends in schizophrenia treatment

Prof. Llorca talks about functioning and innovative approaches to schizophrenia treatment.

Watch the full interview here

    Treating Schizophrenia

    The goal of schizophrenia treatment is to reduce the frequency and severity of psychotic episodes, as well as to improve the functional capacity and quality of life of individuals with schizophrenia, ultimately resulting in patient recovery and reintegration.

    Treatment Goals

    References

    1. Haller, C. S., Padmanabhan, J. L., Lizano, P., Torous, J. & Keshavan, M. Recent advances in understanding schizophrenia. F1000Prime Rep. 6, 1–11 (2014).
    The goals of treating schizophrenia
    The goals of treating schizophrenia


    The Challenge of Negative Symptoms in Schizophrenia

    Negative symptoms can be difficult to recognize as part of schizophrenia, they are rarely the reason patients seek help, and treatment remains a challenge for patients with these complicated and heterogeneous symptoms 1,2.

    Negative Symptoms Across the Disease

    References

    1. National Institutes of Mental Health (NIMH). Schizophrenia. (2017). Available at: https://www.nimh.nih.gov/health/publications/schizophrenia-booklet/index.shtml.
    2. Fischer, B. A. & Buchanan, R. W. Schizophrenia: Clinical Manifestations, Course, Assessment and Diagnosis. UpToDate (2017). Available at: www.up-to-date/schizophrenia.
    3. Lieberman, J. A. Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective. Biol. Psychiatry 50, 884–897 (2001).

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    ANTIPSYCHOTICS, DIFFERENT MOAS?

    The clinical efficacy profile of typical antipsychotic agents appears to depend on high affinity for and full antagonist activity at dopamine D2 receptors. Due

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